The Forkhead Box Protein N1 (FOXN1) Antibody from Abbexa Ltd is a Rabbit Polyclonal antibody to FOXN1. This antibody recognizes Homo Sapiens, and Human antigen. The Forkhead Box Protein N1 (FOXN1) Antibody has been validated for the following applications: EIA, Immunoassay, ELISA, Flow Cytometry, and Western Blot.
Description
Mutations in the winged-helix transcription factor gene at the nude locus in mice and rats produce the pleiotropic phenotype of hairlessness and athymia, resulting in a severely compromised immune system. This gene is orthologous to the mouse and rat genes and encodes a similar DNA-binding transcription factor that is thought to regulate keratin gene expression. A mutation in this gene has been correlated with T-cell immunodeficiency, the skin disorder congenital alopecia, and nail dystrophy. Alternative splicing in the 5' UTR of this gene has been observed. [provided by RefSeq]